Background: Shigellosis and salmonellosis are still global health problems, especially, in developing countries where poor sanitation, lack of clean water supply and proper sewage disposal system exist. The emergence of increased antimicrobial resistance of Shigella and Salmonella species are global challenges, particularly in developing countries like Ethiopia where increased misuse of antimicrobial agents by human beings occur. Objectives: To determine the prevalence and antimicrobial susceptibility patterns of Shigella and Salmonella isolates from patients with diarrhea attending the health institutions in Gondar town, Northwest Ethiopia. Materials and Methods: Health institutional based cross sectional study was carried out on diarrheic patients attending Gondar town health institutions, February 29, 2014 to May 20, 2014. Systematic random sampling technique was used and stool samples were collected from 372 study subjects. Samples were cultured onto MacConkey and Salmonella-Shigella agars and drug susceptibility patterns of the isolates were determined following standard bacteriological method. Data were coded and entered for statistical analysis using SPSS version 20. Data were presented using tables and chi-square. Result: Of the total of 372 stool cultures, 17(4.57%) Shigella spp. and 4(1.08%) Salmonella spp. were isolated. Most commonly isolated strains of Shigella were S. flexneri 11(64.7%) followed by S. dysenteriae 3(17.65%), S. boydii 2(11.77%) and S. sonnei 1(5.88%). Shigella isolates presented high resistance rate to ampicilin (94.1%), amoxicillin (88.2), tetracycline (88.2%) and Salmonella species were highly resistance to tetracycline (100%), amoxicillin (100%), and ampicillin (75%). However, all isolates of Shigella and Salmonella were 100% susceptible to ciprofloxacin and norfloxacin. Conclusion and recommendation: This study revealed that isolates of Shigella and Salmonella showed high rate of drug resistance to the commonly used antibiotics. However, all the isolates were susceptible to ciprofloxacin, and norfloxacin. Therefore, ciprofloxacin and norfloxacin can be used as drugs of choice for the treatment of Shigellosis and Salmonellosis.
| Published in | Science Journal of Public Health (Volume 2, Issue 5) |
| DOI | 10.11648/j.sjph.20140205.24 |
| Page(s) | 469-475 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2014. Published by Science Publishing Group |
Antibiotic Susceptibility, Prevalence, Salmonella and Shigella
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APA Style
Tesfaye Andualem Demissie, Moges Tiruneh Wubie, Feleke Moges Yehuala, Dagnachew Muluye Fetene, Getnet Ayalew Gudeta. (2014). Prevalence and Antimicrobial Susceptibility Patterns of Shigella and Salmonella Species among Patients with Diarrhea Attending Gondar Town Health Institutions, Northwest Ethiopia. Science Journal of Public Health, 2(5), 469-475. https://doi.org/10.11648/j.sjph.20140205.24
ACS Style
Tesfaye Andualem Demissie; Moges Tiruneh Wubie; Feleke Moges Yehuala; Dagnachew Muluye Fetene; Getnet Ayalew Gudeta. Prevalence and Antimicrobial Susceptibility Patterns of Shigella and Salmonella Species among Patients with Diarrhea Attending Gondar Town Health Institutions, Northwest Ethiopia. Sci. J. Public Health 2014, 2(5), 469-475. doi: 10.11648/j.sjph.20140205.24
AMA Style
Tesfaye Andualem Demissie, Moges Tiruneh Wubie, Feleke Moges Yehuala, Dagnachew Muluye Fetene, Getnet Ayalew Gudeta. Prevalence and Antimicrobial Susceptibility Patterns of Shigella and Salmonella Species among Patients with Diarrhea Attending Gondar Town Health Institutions, Northwest Ethiopia. Sci J Public Health. 2014;2(5):469-475. doi: 10.11648/j.sjph.20140205.24
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Download@article{10.11648/j.sjph.20140205.24,
author = {Tesfaye Andualem Demissie and Moges Tiruneh Wubie and Feleke Moges Yehuala and Dagnachew Muluye Fetene and Getnet Ayalew Gudeta},
title = {Prevalence and Antimicrobial Susceptibility Patterns of Shigella and Salmonella Species among Patients with Diarrhea Attending Gondar Town Health Institutions, Northwest Ethiopia},
journal = {Science Journal of Public Health},
volume = {2},
number = {5},
pages = {469-475},
doi = {10.11648/j.sjph.20140205.24},
url = {https://doi.org/10.11648/j.sjph.20140205.24},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.sjph.20140205.24},
abstract = {Background: Shigellosis and salmonellosis are still global health problems, especially, in developing countries where poor sanitation, lack of clean water supply and proper sewage disposal system exist. The emergence of increased antimicrobial resistance of Shigella and Salmonella species are global challenges, particularly in developing countries like Ethiopia where increased misuse of antimicrobial agents by human beings occur. Objectives: To determine the prevalence and antimicrobial susceptibility patterns of Shigella and Salmonella isolates from patients with diarrhea attending the health institutions in Gondar town, Northwest Ethiopia. Materials and Methods: Health institutional based cross sectional study was carried out on diarrheic patients attending Gondar town health institutions, February 29, 2014 to May 20, 2014. Systematic random sampling technique was used and stool samples were collected from 372 study subjects. Samples were cultured onto MacConkey and Salmonella-Shigella agars and drug susceptibility patterns of the isolates were determined following standard bacteriological method. Data were coded and entered for statistical analysis using SPSS version 20. Data were presented using tables and chi-square. Result: Of the total of 372 stool cultures, 17(4.57%) Shigella spp. and 4(1.08%) Salmonella spp. were isolated. Most commonly isolated strains of Shigella were S. flexneri 11(64.7%) followed by S. dysenteriae 3(17.65%), S. boydii 2(11.77%) and S. sonnei 1(5.88%). Shigella isolates presented high resistance rate to ampicilin (94.1%), amoxicillin (88.2), tetracycline (88.2%) and Salmonella species were highly resistance to tetracycline (100%), amoxicillin (100%), and ampicillin (75%). However, all isolates of Shigella and Salmonella were 100% susceptible to ciprofloxacin and norfloxacin. Conclusion and recommendation: This study revealed that isolates of Shigella and Salmonella showed high rate of drug resistance to the commonly used antibiotics. However, all the isolates were susceptible to ciprofloxacin, and norfloxacin. Therefore, ciprofloxacin and norfloxacin can be used as drugs of choice for the treatment of Shigellosis and Salmonellosis.},
year = {2014}
}
TY - JOUR T1 - Prevalence and Antimicrobial Susceptibility Patterns of Shigella and Salmonella Species among Patients with Diarrhea Attending Gondar Town Health Institutions, Northwest Ethiopia AU - Tesfaye Andualem Demissie AU - Moges Tiruneh Wubie AU - Feleke Moges Yehuala AU - Dagnachew Muluye Fetene AU - Getnet Ayalew Gudeta Y1 - 2014/09/20 PY - 2014 N1 - https://doi.org/10.11648/j.sjph.20140205.24 DO - 10.11648/j.sjph.20140205.24 T2 - Science Journal of Public Health JF - Science Journal of Public Health JO - Science Journal of Public Health SP - 469 EP - 475 PB - Science Publishing Group SN - 2328-7950 UR - https://doi.org/10.11648/j.sjph.20140205.24 AB - Background: Shigellosis and salmonellosis are still global health problems, especially, in developing countries where poor sanitation, lack of clean water supply and proper sewage disposal system exist. The emergence of increased antimicrobial resistance of Shigella and Salmonella species are global challenges, particularly in developing countries like Ethiopia where increased misuse of antimicrobial agents by human beings occur. Objectives: To determine the prevalence and antimicrobial susceptibility patterns of Shigella and Salmonella isolates from patients with diarrhea attending the health institutions in Gondar town, Northwest Ethiopia. Materials and Methods: Health institutional based cross sectional study was carried out on diarrheic patients attending Gondar town health institutions, February 29, 2014 to May 20, 2014. Systematic random sampling technique was used and stool samples were collected from 372 study subjects. Samples were cultured onto MacConkey and Salmonella-Shigella agars and drug susceptibility patterns of the isolates were determined following standard bacteriological method. Data were coded and entered for statistical analysis using SPSS version 20. Data were presented using tables and chi-square. Result: Of the total of 372 stool cultures, 17(4.57%) Shigella spp. and 4(1.08%) Salmonella spp. were isolated. Most commonly isolated strains of Shigella were S. flexneri 11(64.7%) followed by S. dysenteriae 3(17.65%), S. boydii 2(11.77%) and S. sonnei 1(5.88%). Shigella isolates presented high resistance rate to ampicilin (94.1%), amoxicillin (88.2), tetracycline (88.2%) and Salmonella species were highly resistance to tetracycline (100%), amoxicillin (100%), and ampicillin (75%). However, all isolates of Shigella and Salmonella were 100% susceptible to ciprofloxacin and norfloxacin. Conclusion and recommendation: This study revealed that isolates of Shigella and Salmonella showed high rate of drug resistance to the commonly used antibiotics. However, all the isolates were susceptible to ciprofloxacin, and norfloxacin. Therefore, ciprofloxacin and norfloxacin can be used as drugs of choice for the treatment of Shigellosis and Salmonellosis. VL - 2 IS - 5 ER -
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