Five Years Trend of <i>Helicobacter Pylori</i> Infection Among Dyspeptic Patients in Asella Teaching and Referral Hospital, Arsi University, Ethiopia

Million Getachew Mesfun; Shimels Teshome; Desalegn Alemu

doi:doi:10.11648/j.sjcm.20180705.11

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Five Years Trend of Helicobacter Pylori Infection Among Dyspeptic Patients in Asella Teaching and Referral Hospital, Arsi University, Ethiopia

Million Getachew Mesfun, Shimels Teshome, Desalegn Alemu

Published in Science Journal of Clinical Medicine (Volume 7, Issue 5)

Received: 9 October 2018 Accepted: 29 November 2018 Published: 18 December 2018

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Abstract

Infectious diseases such as H. pylori infection are major public health problems in Ethiopia. Even though there are a considerably large number of dyspeptic patients in Asella teaching and referral hospital, there is no study done to assess the trend of H. pylori infection among dyspeptic patients. The objective of this study was to assess a five years trend of H. pylori infection among dyspeptic patients in Asella teaching and referral hospital. A retrospective cross-sectional study design was used to assess the trend of H. pylori infection from January 1, 2013 until October 30, 2017 among dyspeptic patients by counting stool antigen test results from the laboratory log book. It was found that a total of 9,493 dyspeptic patients with the mean age of 33.9 (SD+15.1) years were test for H. pylori infection in the last five years in Asella teaching and referral hospital. The total prevalence of H. pylori was 1,444 (15.2%) in which 863 (59.8%) of them were females and 581 (40.2%) were males. There was a fluctuating trend of H. pylori with annual total cases of H. pylori ranged from 19.3% in 2017 to 6.1% in 2015. The study showed that there was low prevalence of H. pylori infection among dyspeptic patients in Asella teaching and referral hospital, Ethiopia. The low prevalence reported from this study could be also due to the quality of the test kits, therefore, there is a need to validate the test kits used by the hospital laboratory.

Published in	Science Journal of Clinical Medicine (Volume 7, Issue 5)
DOI	10.11648/j.sjcm.20180705.11
Page(s)	37-40
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2018. Published by Science Publishing Group

Keywords

H. pylori, Trend, Dyspeptic Patients, Asella, Ethiopia

References

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[2]	Kusters JG, van Vliet AHM, Kuipers EJ. Pathogenesis of Helicobacter pylori Infection. Clinical Microbiology Reviews. 2006; 19(3): 449-490. doi: http://dx.doi. org/10.1128/CMR.00054-05.
[3]	Percival SL. The Significance of Helicobacter Pylori Acquisition and the Hygiene Hypothesis. In: Microbiology and Aging: Clinical Manifestations. Totowa, NJ: Humana Press. New York: Springer; 2009; 263-274.
[4]	Thomas JE, Dale A, Harding M, Coward WA, Cole TJ, Weaver LT. Helicobacter pylori Colonization in Early Life. Pediatric Research. 1999; 45(2): 218-223. doi: http://dx.doi.org/10.1203/00006450-199902000-00010.
[5]	Kusters, J. G., A. H. M. van Vliet, and E. J. Kuipers, Pathogenesis of Helicobacter pylori Infection. Clinical Microbiology Reviews, 2006; 19(3): 449-490. doi: http:// dx.doi.org/10.1128/cmr.00054-05.
[6]	Kibru D, Gelaw B, Alemu A, Addis Z. Helicobacter pylori infection and its association with anemia among adult dyspeptic patients attending Butajira Hospital, Ethiopia. BMC Infectious Diseases. 2014; 14(1). doi: http://dx.doi.org/10.1186/s12879-014-0656-3.
[7]	Tadesse E, Daka D, Yemane D, Shimelis T. Seroprevalence of Helicobacter pylori infection and its related risk factors in symptomatic patients in southern Ethiopia. BMC Research Notes. 2014; 7(1): 834. doi: http://dx.doi.org/10.1186/1756-0500-7-834.
[8]	Mathewos B, Moges B, Dagnew M. Seroprevalence and trend of Helicobacter pylori infection in Gondar University Hospital among dyspeptic patients, Gondar, North West Ethiopia. BMC Research Notes. 2013; 6(1): 346. doi: http://dx.doi.org/10.1186/1756-0500-6-346.
[9]	Watanabe M, Ito H, Hosono S, et al. Declining trends in prevalence of Helicobacter pylori infection by birth year in a Japanese population. Cancer Sci. 2015; 106(12): 1738-1743. doi: http://dx.doi. org/10.1111/cas.12821
[10]	Workineh M, Andargie D. A 5-year trend of Helicobacter pylori seroprevalence among dyspeptic patients at Bahir Dar Felege Hiwot Referral Hospital, Northwest Ethiopia. Research and Reports in Tropical Medicine. 2016; Volume 7: 17-22. doi: http://dx.doi. org/10.2147/RRTM.S105361.
[11]	Abebaw W, Kibret M, Abera B. Prevalence and Risk Factors of H. pylori from Dyspeptic Patients in Northwest Ethiopia: A Hospital Based Cross-sectional Study. Asian Pacific Journal of Cancer Prevention. 2014; 15(11): 4459-4463. doi: http://dx.doi. org/10.7314/APJCP.2014.15.11.4459.
[12]	Negash, M., H. Wondifraw Baynes, and D. Geremew, Helicobacter pylori Infection and Its Risk Factors: A Prospective Cross-Sectional Study in Resource-Limited Settings of Northwest Ethiopia. The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale, 2018. 2018: p. 9463710-9463710.
[13]	Asrat D, Nilsson I, Mengistu Y, et al. Prevalence of Helicobacter pylori infection among adult dyspeptic patients in Ethiopia. Ann Trop Med Parasitol. 2004; 98(2): 181-189. doi: http://dx.doi. org/10.1179/000349804225003190.
[14]	Lim SH, Kwon J-W, Kim N, et al. Prevalence and risk factors of Helicobacter pylori infection in Korea: Nationwide multicenter study over 13 years. BMC Gastroenterology. 2013; 13(1). doi: http://dx.doi. org/10.1186/1471-230X-13-104.
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APA Style

Million Getachew Mesfun, Shimels Teshome, Desalegn Alemu. (2018). Five Years Trend of Helicobacter Pylori Infection Among Dyspeptic Patients in Asella Teaching and Referral Hospital, Arsi University, Ethiopia. Science Journal of Clinical Medicine, 7(5), 37-40. https://doi.org/10.11648/j.sjcm.20180705.11

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ACS Style

Million Getachew Mesfun; Shimels Teshome; Desalegn Alemu. Five Years Trend of Helicobacter Pylori Infection Among Dyspeptic Patients in Asella Teaching and Referral Hospital, Arsi University, Ethiopia. Sci. J. Clin. Med. 2018, 7(5), 37-40. doi: 10.11648/j.sjcm.20180705.11

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AMA Style

Million Getachew Mesfun, Shimels Teshome, Desalegn Alemu. Five Years Trend of Helicobacter Pylori Infection Among Dyspeptic Patients in Asella Teaching and Referral Hospital, Arsi University, Ethiopia. Sci J Clin Med. 2018;7(5):37-40. doi: 10.11648/j.sjcm.20180705.11

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@article{10.11648/j.sjcm.20180705.11,
  author = {Million Getachew Mesfun and Shimels Teshome and Desalegn Alemu},
  title = {Five Years Trend of Helicobacter Pylori Infection Among Dyspeptic Patients in Asella Teaching and Referral Hospital, Arsi University, Ethiopia},
  journal = {Science Journal of Clinical Medicine},
  volume = {7},
  number = {5},
  pages = {37-40},
  doi = {10.11648/j.sjcm.20180705.11},
  url = {https://doi.org/10.11648/j.sjcm.20180705.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.sjcm.20180705.11},
  abstract = {Infectious diseases such as H. pylori infection are major public health problems in Ethiopia. Even though there are a considerably large number of dyspeptic patients in Asella teaching and referral hospital, there is no study done to assess the trend of H. pylori infection among dyspeptic patients. The objective of this study was to assess a five years trend of H. pylori infection among dyspeptic patients in Asella teaching and referral hospital. A retrospective cross-sectional study design was used to assess the trend of H. pylori infection from January 1, 2013 until October 30, 2017 among dyspeptic patients by counting stool antigen test results from the laboratory log book. It was found that a total of 9,493 dyspeptic patients with the mean age of 33.9 (SD+15.1) years were test for H. pylori infection in the last five years in Asella teaching and referral hospital. The total prevalence of H. pylori was 1,444 (15.2%) in which 863 (59.8%) of them were females and 581 (40.2%) were males. There was a fluctuating trend of H. pylori with annual total cases of H. pylori ranged from 19.3% in 2017 to 6.1% in 2015. The study showed that there was low prevalence of H. pylori infection among dyspeptic patients in Asella teaching and referral hospital, Ethiopia. The low prevalence reported from this study could be also due to the quality of the test kits, therefore, there is a need to validate the test kits used by the hospital laboratory.},
 year = {2018}
}

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TY - JOUR
T1 - Five Years Trend of Helicobacter Pylori Infection Among Dyspeptic Patients in Asella Teaching and Referral Hospital, Arsi University, Ethiopia
AU - Million Getachew Mesfun
AU - Shimels Teshome
AU - Desalegn Alemu
Y1 - 2018/12/18
PY - 2018
N1 - https://doi.org/10.11648/j.sjcm.20180705.11
DO - 10.11648/j.sjcm.20180705.11
T2 - Science Journal of Clinical Medicine
JF - Science Journal of Clinical Medicine
JO - Science Journal of Clinical Medicine
SP - 37
EP - 40
PB - Science Publishing Group
SN - 2327-2732
UR - https://doi.org/10.11648/j.sjcm.20180705.11
AB - Infectious diseases such as H. pylori infection are major public health problems in Ethiopia. Even though there are a considerably large number of dyspeptic patients in Asella teaching and referral hospital, there is no study done to assess the trend of H. pylori infection among dyspeptic patients. The objective of this study was to assess a five years trend of H. pylori infection among dyspeptic patients in Asella teaching and referral hospital. A retrospective cross-sectional study design was used to assess the trend of H. pylori infection from January 1, 2013 until October 30, 2017 among dyspeptic patients by counting stool antigen test results from the laboratory log book. It was found that a total of 9,493 dyspeptic patients with the mean age of 33.9 (SD+15.1) years were test for H. pylori infection in the last five years in Asella teaching and referral hospital. The total prevalence of H. pylori was 1,444 (15.2%) in which 863 (59.8%) of them were females and 581 (40.2%) were males. There was a fluctuating trend of H. pylori with annual total cases of H. pylori ranged from 19.3% in 2017 to 6.1% in 2015. The study showed that there was low prevalence of H. pylori infection among dyspeptic patients in Asella teaching and referral hospital, Ethiopia. The low prevalence reported from this study could be also due to the quality of the test kits, therefore, there is a need to validate the test kits used by the hospital laboratory.
VL - 7
IS - 5
ER -

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Author Information

Million Getachew Mesfun

Department of Medical Laboratory Science, college of Health Sciences, Arsi University, Asella, Ethiopia
Shimels Teshome

Asella Teaching and Referral Hospital, Arsi University, Asella, Ethiopia
Desalegn Alemu

Asella Teaching and Referral Hospital, Arsi University, Asella, Ethiopia

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APA Style

Million Getachew Mesfun, Shimels Teshome, Desalegn Alemu. (2018). Five Years Trend of Helicobacter Pylori Infection Among Dyspeptic Patients in Asella Teaching and Referral Hospital, Arsi University, Ethiopia. Science Journal of Clinical Medicine, 7(5), 37-40. https://doi.org/10.11648/j.sjcm.20180705.11

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ACS Style

Million Getachew Mesfun; Shimels Teshome; Desalegn Alemu. Five Years Trend of Helicobacter Pylori Infection Among Dyspeptic Patients in Asella Teaching and Referral Hospital, Arsi University, Ethiopia. Sci. J. Clin. Med. 2018, 7(5), 37-40. doi: 10.11648/j.sjcm.20180705.11

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AMA Style

Million Getachew Mesfun, Shimels Teshome, Desalegn Alemu. Five Years Trend of Helicobacter Pylori Infection Among Dyspeptic Patients in Asella Teaching and Referral Hospital, Arsi University, Ethiopia. Sci J Clin Med. 2018;7(5):37-40. doi: 10.11648/j.sjcm.20180705.11

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@article{10.11648/j.sjcm.20180705.11,
  author = {Million Getachew Mesfun and Shimels Teshome and Desalegn Alemu},
  title = {Five Years Trend of Helicobacter Pylori Infection Among Dyspeptic Patients in Asella Teaching and Referral Hospital, Arsi University, Ethiopia},
  journal = {Science Journal of Clinical Medicine},
  volume = {7},
  number = {5},
  pages = {37-40},
  doi = {10.11648/j.sjcm.20180705.11},
  url = {https://doi.org/10.11648/j.sjcm.20180705.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.sjcm.20180705.11},
  abstract = {Infectious diseases such as H. pylori infection are major public health problems in Ethiopia. Even though there are a considerably large number of dyspeptic patients in Asella teaching and referral hospital, there is no study done to assess the trend of H. pylori infection among dyspeptic patients. The objective of this study was to assess a five years trend of H. pylori infection among dyspeptic patients in Asella teaching and referral hospital. A retrospective cross-sectional study design was used to assess the trend of H. pylori infection from January 1, 2013 until October 30, 2017 among dyspeptic patients by counting stool antigen test results from the laboratory log book. It was found that a total of 9,493 dyspeptic patients with the mean age of 33.9 (SD+15.1) years were test for H. pylori infection in the last five years in Asella teaching and referral hospital. The total prevalence of H. pylori was 1,444 (15.2%) in which 863 (59.8%) of them were females and 581 (40.2%) were males. There was a fluctuating trend of H. pylori with annual total cases of H. pylori ranged from 19.3% in 2017 to 6.1% in 2015. The study showed that there was low prevalence of H. pylori infection among dyspeptic patients in Asella teaching and referral hospital, Ethiopia. The low prevalence reported from this study could be also due to the quality of the test kits, therefore, there is a need to validate the test kits used by the hospital laboratory.},
 year = {2018}
}

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