Secondary cataract is the most common postoperative complication, which causes repeated significant reduced visual acuity, even after a successful operation on the lens. Due to significant clinical heterogeneity of secondary cataract of a man a comparative morphological and functional study in the formation of its fibrous and proliferative forms is especially important for identification of pathogenesis foundations of this disease. The used morphological, histochemical and clinical techniques in the conducted study have provided some evidence of the important role of trophic nervous influences on the type formation of secondary cataract in humans. It is important to note that the revealed similarities in changes of bioamine status, immunoreactivity of the epithelium and fibers of the human crystalline lens in different types of age-related cataract (cortical and nuclear) and its postoperative complications (proliferative and fibrous types of secondary cataract, respectively) can serve as an important proof of their common pathogenesis and, consequently, the type of age-related cataract can be offered as an accessible marker for predicting the risk of postoperative secondary cataract of certain type and its early prevention. The results allow for the first time to put forward a new concept of the secondary cataract pathogenesis. The presented in this chapter concept emphasizes the importance of the fundamental problems of medicine – maintaining the stability of tissue differentiation of a living organism in a variety of physiological and pathological conditions, under the influence of neurotrophic factors.
| Published in | International Journal of Immunology (Volume 5, Issue 5) |
| DOI | 10.11648/j.iji.20170505.11 |
| Page(s) | 80-87 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2017. Published by Science Publishing Group |
Secondary Cataract, Age-Related Cataract, Pathogenesis, Autonomic Nervous System, Neurotransmitters, Phenotype
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APA Style
Nadezhda Vitalievna Korsakova. (2017). New Fluorescent-Histochemical and Immuno-Histochemical Aspects of Secondary Cataract Pathogenesis in Humans. International Journal of Immunology, 5(5), 80-87. https://doi.org/10.11648/j.iji.20170505.11
ACS Style
Nadezhda Vitalievna Korsakova. New Fluorescent-Histochemical and Immuno-Histochemical Aspects of Secondary Cataract Pathogenesis in Humans. Int. J. Immunol. 2017, 5(5), 80-87. doi: 10.11648/j.iji.20170505.11
AMA Style
Nadezhda Vitalievna Korsakova. New Fluorescent-Histochemical and Immuno-Histochemical Aspects of Secondary Cataract Pathogenesis in Humans. Int J Immunol. 2017;5(5):80-87. doi: 10.11648/j.iji.20170505.11
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Download@article{10.11648/j.iji.20170505.11,
author = {Nadezhda Vitalievna Korsakova},
title = {New Fluorescent-Histochemical and Immuno-Histochemical Aspects of Secondary Cataract Pathogenesis in Humans},
journal = {International Journal of Immunology},
volume = {5},
number = {5},
pages = {80-87},
doi = {10.11648/j.iji.20170505.11},
url = {https://doi.org/10.11648/j.iji.20170505.11},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.iji.20170505.11},
abstract = {Secondary cataract is the most common postoperative complication, which causes repeated significant reduced visual acuity, even after a successful operation on the lens. Due to significant clinical heterogeneity of secondary cataract of a man a comparative morphological and functional study in the formation of its fibrous and proliferative forms is especially important for identification of pathogenesis foundations of this disease. The used morphological, histochemical and clinical techniques in the conducted study have provided some evidence of the important role of trophic nervous influences on the type formation of secondary cataract in humans. It is important to note that the revealed similarities in changes of bioamine status, immunoreactivity of the epithelium and fibers of the human crystalline lens in different types of age-related cataract (cortical and nuclear) and its postoperative complications (proliferative and fibrous types of secondary cataract, respectively) can serve as an important proof of their common pathogenesis and, consequently, the type of age-related cataract can be offered as an accessible marker for predicting the risk of postoperative secondary cataract of certain type and its early prevention. The results allow for the first time to put forward a new concept of the secondary cataract pathogenesis. The presented in this chapter concept emphasizes the importance of the fundamental problems of medicine – maintaining the stability of tissue differentiation of a living organism in a variety of physiological and pathological conditions, under the influence of neurotrophic factors.},
year = {2017}
}
TY - JOUR T1 - New Fluorescent-Histochemical and Immuno-Histochemical Aspects of Secondary Cataract Pathogenesis in Humans AU - Nadezhda Vitalievna Korsakova Y1 - 2017/11/28 PY - 2017 N1 - https://doi.org/10.11648/j.iji.20170505.11 DO - 10.11648/j.iji.20170505.11 T2 - International Journal of Immunology JF - International Journal of Immunology JO - International Journal of Immunology SP - 80 EP - 87 PB - Science Publishing Group SN - 2329-1753 UR - https://doi.org/10.11648/j.iji.20170505.11 AB - Secondary cataract is the most common postoperative complication, which causes repeated significant reduced visual acuity, even after a successful operation on the lens. Due to significant clinical heterogeneity of secondary cataract of a man a comparative morphological and functional study in the formation of its fibrous and proliferative forms is especially important for identification of pathogenesis foundations of this disease. The used morphological, histochemical and clinical techniques in the conducted study have provided some evidence of the important role of trophic nervous influences on the type formation of secondary cataract in humans. It is important to note that the revealed similarities in changes of bioamine status, immunoreactivity of the epithelium and fibers of the human crystalline lens in different types of age-related cataract (cortical and nuclear) and its postoperative complications (proliferative and fibrous types of secondary cataract, respectively) can serve as an important proof of their common pathogenesis and, consequently, the type of age-related cataract can be offered as an accessible marker for predicting the risk of postoperative secondary cataract of certain type and its early prevention. The results allow for the first time to put forward a new concept of the secondary cataract pathogenesis. The presented in this chapter concept emphasizes the importance of the fundamental problems of medicine – maintaining the stability of tissue differentiation of a living organism in a variety of physiological and pathological conditions, under the influence of neurotrophic factors. VL - 5 IS - 5 ER -
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